Thursday 15 March 2012

Veterinary Medicine 10th Edition



A textbook of the diseases of cattle, horses, sheep, pigs and goats

By Otto M. Radostits, CM, DVM, MSc, MRCVS, Dipl ACVIM, Clive C. Gay, DVM, MVSc, FACVSc, Kenneth W. Hinchcliff, BVSc(Hons), MS, PhD, Dipl ACVIM and Peter D. Constable, BVSc, MS, PhD, Dipl ACVIM

The new 10th edition of this well-respected reference includes thoroughly revised and reviewed information with content on new diseases for the most up-to-date information on diseases effecting sheep, pigs, goats, horses, and cattle. Divided into two sections, General Medicine and Special Medicine, the book covers topics ranging from the clinical examination and manifestation of disease in organ systems to specific diseases of the large animal species.

CONTENTS


List of tables...... .. .vii
List of illustrations ..ix
List of contributors. x
. . .. .. .. . . .
Preface to Tenth Edition... .xiii
Introduction .....xv
How to use this book.. ....xxi
PART ONE: GENE RA L MED ICINE
.
1 Clinical examination and making
a diagnosis .......... ....... ..3
Clinical examination of the individual
animal .... ...... .. .. .... ....3
.
Making a diagnosis .. ............22
Prognosis and therapeutic
decision-making ...... ......... 29
Examination of the herd .......... 31
.
2 General systemic states .........39
Hypothermia, hyperthermia, fever ...39
Septicemia/viremia ....... ... ...5 1
.
Toxemia and endotoxemia ... ...... 5 3
Hypovolemic, hemorrhagic,
maldistributive and obstructive
shock . ...... .. ... .... .......6 3
Allergy and anaphylaxis ...........6 9
Edema .......... .... ... . .....72
Disturbances of free water,
electrolytes and acid-base balance ..73
Pain .. ......... ...... ...... 102.
Stress .... .............. ... .. 107
Localized infections .... ..... .. ..110
Disturbances of appetite, food
intake and nutritional status . .... 112
Weight loss or failure to gain
weight (ill -thrift) ........115
Physical exercise and associated
disorders ............ .. .. .. .117
Diagnosis and care of recumbent
adult horses......... .. 120
.
Sudden or unexpected death ......124
.
3 Diseases of the newborn ....... 127
Perinatal and postnatal diseases . .. 127
.
Congenital defects .... ......... 1 3 2
Physical and environmental causes
of perinatal disease ...138
Diseases of cloned offspring.145
Neonatal infection......... ... 146
.
Clinical assessment and care of
critically ill newborns . . ..160
4. P r actical antimicrobial
therap eutics ......... ....... 173
Principles of antimicrobial therapy .. 173
Practical usage of antimicrobial
drugs . .. .. .. .. .. .. ... .. .177
tract - I . .. ........ ......... 189
Principles of alimentary tract
dysfunction ................ .189
Manifestations of alimentary tract
dysfunction......... .. ... ... 191
Special examination ..... ... ... . 195
Principles of treatment in alimentary
tract disease . . ....... .......203
.
Diseases of the buccal cavity and
associated organs . ... ...... ... 205
Diseases of the pharynx and
esophagus ... . . . ...... ..209
Diseases of the nonruminant
stomach and intestines ......215
Congenital defects of the alimentary
tract ... . ...................280
Neoplasms of the alimentary tract .. 28 1
Diseases of the peritoneum . ......28 2
.
6 Diseases of the alimentary
tract - II ...................293
Diseases of the forestomach of
ruminants ..... ............. .293
Special examination of the
alimentary tract and abdomen of
cattle ..... ....... ..........301
Diseases of the rumen, reticulum
and omasum ................3 11
Diseases of the abomasum . ......3 5 3
Diseases of the intestines of
ruminants ....... ............375
.
7 Diseases o f the liver and
pancreas ........ ...........38 3
Diseases of the liver - introduction .383
Principles of hepatic dysfunction . .38 3
.
Manifestations of liver and biliary
disease .. ........... .......384
.
Special examination of the liver ....387
Principles of treatment in diseases
of the liver ..................391
Diffuse diseases of the liver ...... .391
Focal diseases of the liver ... .....395
Diseases of the pancreas .... .....396
.
8 Diseases of the cardiovascular
system ............. ........ 399
Principles of circulatory failure ..... 399
Manifestations of circulatory
failure .. ... ............. ...401
Special examination of the
cardiovascular system ......... .405
Arrhythmias ........... .4 1 3
Diseases of the heart .. ........ .421
Diseases of the blood vessels . .... .4 3 4
9. Diseases of the hemolymphatic and
immune systems .. ... ....... .439
Abnormalities of plasma protein
concentration ..... .......... .439
Hemorrhagic disease ...... ...... 441
Disorders of red cell number or
function ........ ..... ... .. .4 5 0
.
Disorders o f white cells .... ......460
Lymphadenopathy (lymphadenitis) . .46 4
Diseases of the spleen and
thymus .... ................ .464
Immune deficiency disorders (lowered
resistance to infection) ........ .466
Amyloidoses ........ ... .. .....467
Porphyrias ............... ....469
.
10 Diseases of the respiratory
system ............... ..... .471
Principles of respiratory
insufficiency ..... . ... ........471
Principal manifestations of respiratory
insufficiency .................473
Special examination of the respiratory
system . .. ........... . ......480
Principles of treatment and control of
respiratory tract disease ..... .. .493
.
Diseases of the lungs .. .. . ......498
Diseases of the pleura and
d�ph�gm . ... ..... ....... .5 19
.
Diseases of the upper respiratory
tract . .. .. .... ........5 30
.
1 1 Diseases of the urinary system ...543
Introduction ..................543
Principles of renal insufficiency....543
Clinical features of urinary tract
disease .......... ........... 5 4 5
Special examination of the urinary
system .... ..... .......... ..5 48
Principles of treatment of urinary
tract disease .. ............... 553
Diseases of the kidney. .........5 55
Diseases of the bladder, ureters and
urethra ....... ...... ........56 1
Congenital defects of the urinary
tract ... .. .............. ....571
1 2 Diseases of the nervous
.
system .....................575
Principles of nervous dysfunction . ..576
Clinical manifestations of disease
of the nervous system . ......... 5 77
Special examination of the nervous
system ....... ............. .583
Principles of treatment of diseases
of the nervous system ..........594
Pathophysiological mechanisms
of nervous system disease ...... .596
Diffuse diseases of the brain ......596
Focal diseases of the brain.......606
Diseases of the meninges ...... ..609
Toxic and metabolic
encephalomyelopathies .........6 1 1
Psychoses or neuroses ...........6 1 2
Epilepsy ............ ..... ....6 1 3
Diseases o f the spinal cord ....... 6 1 3
Diseases o f the peripheral nervous
system ....... .... .. ........6 18
Congenital defects of the central
nervous system': ..............6 19
1 3. Diseases of the musculoskeletal
system .. ... .............. ..621
Principal manifestations of
musculoskeletal disease .. ......621
.
Diseases of muscles...... ......6 26
Diseases of bones .. .. . ......6 3 2
Diseases o f joints ..............6 3 7
Congenital defects o f muscles,
bones and joints ..............648
.
14 Diseases of the skin, conjunctiva
and external ear .......... ...651
Principles of treatment of diseases
of the skin ....... ........ ...6 5 3
Diseases of the epidermis and
dermis ............... ... ..6 5 4.
Diseases of the hair, wool, follicles,
skin glands, horns and
hooves ........... ..........66 1
Diseases of the subcutis....... ..66 4
Granulomatous lesions of the
skin ............. . .... ..... 667
Cutaneous neoplasms ......... ..66 7
Congenital defects of the skin .....669
Congenital skin neoplasms ... ....�6 9
Diseases of the conjunctiva ....... 6 70
Congenital defects of the eyelids
and cornea ..................670
Diseases of the external ear ....... 6 70
15 Diseases of the mammary
.
gland ..... .............. ..6 73
Introduction ..... .. ...........6 73
Bovine mastitis .... .. ......673
Mastitis pathoqens of cattle ......697
Mastitis of cattle associated with
common contagious pathogens . .. 697
Mastitis associated with teat skin
opportunistic pathogens ... .708
Mastitis of cattle associated with
common environmental
pathogens ..... . . ... .. .. . ..709
.
Mastitis of cattle associated with
less common pathogens .... .. . .724
Miscellaneous causes of bovine
mastitis... ....726
Control of bovine mastitis. .. ..728
Miscellaneous abnormalities of the
teats and udder.... .749
Mastitis-metritis-aga lactia
syndrome in sows ..... . . . 754
Mastitis of sheep. . ..
. .....759
Mastitis of goats ...761
Mastitis of mares.. ...762
Mastitis of cattle associated with
common contagious pathogens . .. 697
Mastitis associated with teat skin
opportunistic pathogens ... .708
Mastitis of cattle associated with
common environmental
pathogens ..... . . ... .. .. . ..709
.
Mastitis of cattle associated with
less common pathogens .... .. . .724
Miscellaneous causes of bovine
mastitis... ....726
Control of bovine mastitis. .. ..728
Miscellaneous abnormalities of the
teats and udder.... .749
Mastitis-metritis-aga lactia
syndrome in sows ..... . . . 754
Mastitis of sheep. . ..
. .....759
Mastitis of goats ...761
Mastitis of mares.. ...762
Mastitis of cattle associated with
common contagious pathogens . .. 697
Mastitis associated with teat skin
opportunistic pathogens ... .708
Mastitis of cattle associated with
common environmental
pathogens ..... . . ... .. .. . ..709
.
Mastitis of cattle associated with
less common pathogens .... .. . .724
Miscellaneous causes of bovine
mastitis... ....726
Control of bovine mastitis. .. ..728
Miscellaneous abnormalities of the
teats and udder.... .749
Mastitis-metritis-aga lactia
syndrome in sows ..... . . . 754
Mastitis of sheep. . ..
. .....759
Mastitis of goats ...761
Mastitis of mares.. ...762
Mastitis of cattle associated with
common contagious pathogens . .. 697
Mastitis associated with teat skin
opportunistic pathogens ... .708
Mastitis of cattle associated with
common environmental
pathogens ..... . . ... .. .. . ..709
.
Mastitis of cattle associated with
less common pathogens .... .. . .724
Miscellaneous causes of bovine
mastitis... ....726
Control of bovine mastitis. .. ..728
Miscellaneous abnormalities of the
teats and udder.... .749
Mastitis-metritis-aga lactia
syndrome in sows ..... . . . 754
Mastitis of sheep. . ..
. .....759
Mastitis of goats ...761
Mastitis of mares.. ...762

PART TWO: SPE C I AL MED I C IN E
16. Diseases associated with
bacteria - I. .. .............
.765
Introduction to infectious
disease . .
. ... . . .
. . .. 765
Diseases associated with
Streptococcus species.768
Diseases associated with
Staphylococcus species.78 3
D·lseases associated with
Corynebacterium, Rhodococcus,
Actinobaculum and Arcanobacterium
species.
. .. . . .. .. ..787
Diseases associated with Listeria
species. .. .. . . . . . .805
Diseases associated with Erysipelothrix
rhusiopathiae (insidiosa ).. 810
.
Diseases associated with
Bacillus species. . .. . . ... .815
..
.
17 Diseases associated with
.
bacteria - II ..... . ... . ... .
.. 821
Diseases associated with Clostridium
species. . .. 821
.
18. Diseases associated with
bacteria-III.... ....
...
.. ... 847
Diseases associated with
Escherichia coli. 8 47
Escherichia coli infections in
weaned pigs .. .888
Diseases associated with Salmonella
species ..... . . .896
Diseases associated with Pasteurella
species.921
Diseases associated with Brucella
species . ..
.. . . . . 963
Diseases associated with Moraxella,
Histophilus and Haemophilus
species . ...994
19. Diseases associated with
bacteria-..
IV .... ... .. .. 1007
..
Diseases associated with
Mycobacterium spp...... 1007
Diseases associated with Actinomyces,
Actinobacillus, Nocardia and
Dermatophilus spp. . . . . .. .. .. .1044
20. Diseases associated with
bacteria-V..........
.. ... 1061
Diseases associated with Fusobacterium
and Bacteroides spp..
. . . 1061
Diseases associated with Pseudomonas
and Burkholderia spp.. .108 1
Diseases associated with
Campylobacter spp.... 108 5
Diseases associated with
Leptospira Borrelia spp.. .1094
Diseases associated with
Mycoplasma spp. .. . ... ..1123
.
21 Disease associated with viruses
and Chlamydia - I ...........1157
Viral diseases with manifestations
attributable to involvement of the
body as a whole..1157
Viral diseases characterized by
alimentary tract signs.. 1223
.
22. Diseases associated with viruses
and chlamydia-II.
.. ..... ..1307
Viral diseases characterized by
respiratory signs... .1307
Viral diseases characterized by
nervous signs . . .
.. . ..... . 1368
Viral diseases characterized by skin
lesions .. .. ..... . .1418
Diseases associated with
Chlamidiae ....143 3
23. Diseases associated with
prions .. ......
... .........1439
24. Diseases associated with
Rickettsiales........ ... . ..
.1455
.
25 Diseases associated with algae
and fungi.. . .... . ..... .
... 1471
Algal diseases ... .1471
Fungal diseases ... . 1471
Dermatomycoses. . ... . . ..1476
26. Diseases associated with
protozoa.
...... . .... . ...
.1483
Diseases associated with
trypanosomes. ..153 1
27. Diseases associated with
helminth parasites . ..... ....1541
Nematode diseases of the
alimentary tract. .
... ... . ...1541
Nemotode diseases of other
organs .... .. ..1564
Diseases associated with trematodes
and cestodes. .... .1576
28 . Diseases associated with
arthropod parasites .. ..... .. 1585
Ked and louse infestations. . 1596
Tick infestations.. . . . ... .. 1599
..
Miscellaneous flies, midges and
mosquitoes . . ........ 160 3
Mite infestations ....1606
Metabolic diseases .. . .... ..
.. 1613
Production diseases .. . .1618
.
30 Diseases associated with nutritional
. ..
deficiencies .... . .... ... 1691.
Deficiencies of energy and protein .1697
Diseases associated with deficiencies
of mineral nutrients... . . . .. 1698
. .
Disease associated with deficiencies
of fat-soluble vitamins. . . .. . . 1771
. .
Diseases associated with deficiency
of water-soluble vitamins . . . . . ..1778
31. Diseases associated with physical
.
agents ..... . ...... . ......1785
32. Diseases associated with inorganic
and farm chemicals.........1798
Diseases associated with inorganic
poisons . . .. . ..
..1799
Diseases associated with farm
chemicals...... . . ....1830
Miscellaneous farm chemicals.1846
33. Diseases associated with toxins in
plants, fungi, cyanobacteria,
clavibacteria, insects and
.
animals . . .....
..
.. ....... 1851
Diseases associated with major
phytotoxins.1851
Poisoning by mycotoxins....1897
Poisoning by cyanophyte
(cyanobacterial) toxins.1913
Poisoning by tunicaminyluracils
(corynetoxins) ... .. ... .
..1914
Diseases associated with zootoxins
(animal bites and stings) ....1915
34 Diseases associated with
.
.
allergy ... ......... ..... 1921
.
35. Diseases associated with the
inheritance of undesirable
characteristics . . ......
.... ..1937
Diseases characterized by
chromosomal anomalies.. .1939
.
Inherited defects of the body as a
whole. ... . . ....... 1940
Inherited defects of the alimentary
tract ..1943
Inherited defects of the circulatory
system.1944
Inherited defects of the urinary
tract . .
..
. . . . .. ..1948
Inherited defects of the nervous
system. . . ... .
..1948
Inherited defects of the
musculoskeletal system. . 1957
Inherited defects of the skin.1973
Miscellaneous inherited defects .. .1976
36. Specific diseases of uncertain
etiology.
..... ...... .....
.1981
Diseases characterized by systemic
involvement.. .. 198 1
Diseases characterized by alimentary
tract involvement.
... .. . 1988
.
Diseases characterized by respiratory
tract involvement. . . ..1996
.
Diseases characterized by nervous
system involvement.... ... .2004
Diseases characterized by involvement
of the musculoskeletal system.2021
Diseases characterized by involvement
of the skin. ... . 20 35
APPENDICES
Conversion factors..
... . .. . 2045
Reference laboratory values.... .. .. 20 47
Drug doses - horses and ruminants . ..2051
Drug doses - pigs . .. .. . .
.....2064
Index......2067

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